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Hypnotic, antiepileptic, antiparkinsonic agents



1. The patient of 70 years has appealed to the doctor with complaints of superficial short-term sleep with often awakenings caused by sense of internal tension, anxiety, fear. The diagnosis has been made as: senile sleeplessness. Make a rational choice of a hypnotic agent in the given situation.

A.* Nitrazepam

B. Aethaminalum-natrium (pentobarbital)

C. Phenobarbital

D. Bromisovalum

E. Chloral hydrate

2. The patient suffering from parkinsonism has been treating for a long time by the drug with central cholinolytic mechanism of action which efficiency has gradually decreased. Indicate drug which should be administered instead of used one for improving of antiparkinsonic action?

A. * Levodopa

B. Cyclpdolum

C. Mydocalmum

D. Tropacinum

E. Bellataminalum

3. A patient had been suffering from Parkinson's disease was admitted to the neurological department. Indicate the drug inhibitting cholinergic influences which is used for treatment of this disease.

A.*Cyclodolum (trihexyphenidyl)

B. Levodopa

C. Bromocriptin

D. Midantanum (amantadine)

E Selegilin

4. A patient with convulsions was delivered by the ambulance to the hospital where the diagnosis of status epilepticus was given. Indicate the drug of the first choice in this situation.

A. *Diazepam

B. Trimethinum (trimethadione)

C. Phenobarbital

D. Dipheninum (phenytoin)

E.Carbamazepine

5. An attack of generalized tonoclonic convulsions accompanied by loss of consciousness and general suppression of the CNS developed in a patient after trauma. What drug should be administered to this patient?

A. *Phenobarbital

B. Cyclodolum (trihexyphenidyl)

C. Levodopa

D. Teturam (disulflram)

E. Midantanum (amantadine)

6. A 57-years-old woman was admitted to the hospital in coma with inhibition of breathing, decreased BF', signs of cardiac insufficiency, decreased body temperature, inhibition of reflexes. Due to anamnesis she had been suffering from insomnia and a doctor administered to her hypnotic agent. What drug can cause this poisoning?

A. *Phenobarbital

В. Sodium bromide

C. Valeriana tincture

D. Scopolamine

E. Promedolum (trimeperidine)

7. What agent should be administered to a patient in the case of
poisoning by barbiturates to normalize acid-base state?

A. *NaHC03

B. Solution of arginine

C. Vitamins

D. Antibiotics

E. Physiological solution of Natrium

8. A 68-years-old patient was addressed to the doctor in the polyclinic with complaints of mental disorders after usage of Phenobarbital for a long period of time accompanied by insomnia. What drug will the doctor administer to this patient as hypnotic

A. *Nitrazepam

B. Cyclobarbital

C. Chloral hydrate

D. Natrii oxybutyras (oxybate sodium)

E. Halopendol

9. Determine the hypnotic drug which doesn't influence the structure of sleep.

A. *Nitrazepam

B. Phenobarbital

C. Barbital

D. Aethammalum-natrium (pentobarbital)

E. Bromisoval

10. The doctor administered a drug with a tranquilizing effect to the patient with insomnia after emotional disorders. What drug was administered to the patient?

A. *Nitrazepam

B. Phenobarbital

C. Chloral hydrate

D. Aethammalum-natrium (pentobarbital)

E. Bromisoval

11. An 18-years-old patient complained of insomnia which manifested by not being able to sleep that led to fatigue, weakness, difficulty in learning the following day. The clinical examination revealed the following: the patient was easily irritated, emotionally unstable, heart rate and arterial pressure were altered during conversations. The doctor determined that insomnia was associated with a neurosis-like state and vegetovascular distonia. Make the most rational choice of hypnotic drug.

A. *Nitrazepam

B. Phenobarbital

C. Chloral hydrate

D. Aethaminalum-natrium (pentobarbital)

E. Bromisoval

12. A 65-years-old woman with Parkinson's disease has been treated with cyclodolum. Determine the mechanism of action of this drug.

A *Blockade of central cholinoreceptors

B. Stimulation of dopamine receptors

C. Stimulation of serotonine receptor

D. Blockade of histamine receptors

E. Blockade of dopamine receptors

13. Determine the group of drug which can cause medicinal Parkinsonism.

A. *Neuroleptics

B. Hypnotic drugs

C. Antidepressants

D. Tranquilizers

E. Nootropic agents

14. A patient took reserpinum for the treatment of hypertonic disease for a long period of time. One day the patient felt muscles weakness, restriction of motion. Medicamentous parkinsonism was diagnosed. What drug should be administered to eliminate these side effects?

A. *Cyclodolum (trihexyphenidyl)

B. Aminazinum (chlorpromazine)

C. Haloperidolu

P. Phenobarbital

E. Tubocurarine

 




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