Antiprotozoal and anthelmintic agents.

1. A female patient addressed to gynecologist with complaints of undant discharges from vagina with pleasant smell. After bacteriological vestigation the diagnosis of trichmo-•sis has been given. Specify the ug which should be administered.

A. * Metronidazolum (Trichopolum)

В. Sulfadimezinum

C. Chingaminum

D. Chloridinum

E. Monomycinum

2. Mother addressed to the pediatrician with the child who complained of strong itch in the region around the anus, pain intensified at night. After investigation of feaces the diagnosis of enterobiasis was given. Indicate the drug which should be administered.

A. *Levamisolum

B. Trichlorophenum

С. Phenasalum

D. Ditrazinum

E. Aminoacrichinum

3. Indicate the antimalarial agent which is active against paraerythrocytic forms of Plasmodium.

А *Рrimachinum

В Chingaminum

С. Galochinum

D. Hydroxychlorochinum

E. Aminoacrichinum

4. Specify the drug which is used in amebiasis of any localization of pathological process.

A. *Metronidazolum (Trichopolum)

B. Chingaminum

C. Emetinum hydrochloridum

D. Chiniophonum

E. Tetracyciinum

5. A patient visited a physician with complaints of bowel dysfunction. After laboratory examination the diagnosis of lambliasis was made. Specify the drug that should be used.

A. *Metronidazolum (Trichopolum)

B. Tetracycilinum

С. Trichomonacid

D. Monomycinun

E. Chingaminum

6. During summer vacations a student from tropical country developed tertian malaria. After recovery he turned back to Ukraine for study extension. In January an exacerbation was developed, it is known from past history of disease that drug acting on paraerythrocytic plasmodium malariae for prevention of relapse was not prescribed. Indicate the drug:

A. Chingaminum

B. Halochin

С. Hydroxychloroquine

D. Amodiaquine

E. *Primaquine

7. Patient addressed to a physician to get a drug for prevention of malaria. Indicate the drug:

A. *Primaquine

B. Clotrimazole

С. Mebendazole

D. Furazolidone

E. Fenasal

8. What is the mechanism of anthelmintic action of levamisole?

A. *Oppression ot succinate dehydrogenase, ATPase

В. Oppression of MAO

C. DNA synthesis damage

D. Cholinesterase activation

E. Oppression of N-acetyltransferase

9. A drug is administered for prevention and treatment of malaria, treatment of amebiasis and diseases of connective tissue. Indicate the drug.

A. *Chingaminum (chloroquine)

B. Tetracycline

C. Metronidazole

D. Erythromycinum

E. Quinine

10. A drug was administered to a patient with ascaridosis. It is known to have influence on immune system, and is used as immunological modulator. Indicate the drug!

A. *Levamisole

B. Piperazine

С. Pyrantel

D. Phenasaium (niclosamide)

E. Praziquantel

11. A patient complaints of nausea, vomiting, loss of appetite. After investigation of stool ascaridosis was revealed. A drug with immune modulation activity was prescribed for single usage. Indicate the drug:

A. *Levamisole

B. Mebendazole

С. Pyrantel

D. Naphtamonum

E. Piperazine

Antitumoal agents

1. The antitumoral agent from the group of antimetabolites (antagonists of folic acid) was administered to the patient with acute leucosis. Indicate this drug.

A. *Methotrexatum

B. Fluorouracil

C. Myelosanum

D. . Mercaptopurine

E. Hexestrolum

2. Determine a drug for treatment of lympholeukosis:

A. *Embichinum

B. Phthoruracilum

C. Depostat

D. Diethylstilbestrol

E. Phenobolinum

3. A drug belongs to the group of anti-metabolites being an antagonis causes impairment of purines' synthesis, and thus lead to diminishing of nucleic acids' synthesis. Determine the drug:

A. *Methotrexate

B. Mercaptopurine

C. Phthoruracilum (fluorouracil)

D. Cytarabine

E. Cispiatine

4. Antitumoral drug from the group of antimetabolites is used for treatment of leucosis of children and cancer of adults. Determine the drug:

A. *Methotrexate

B. Sarcolysinum

С. Colchamine

D. Rubomycin

E. Prednisolonum

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